SML2593

MS0021570

≥98% (HPLC)

• Sinónimos: 5-(Benzylsulfanyl)-N-methyl-1,3,4-thiadiazol-2-amine, 5-(Benzylthio)-N-methyl-1,3,4-thiadiazol-2-amine, MS 21570, MS0021570_1, N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
• Fórmula empírica (notación de Hill): C₁₀H₁₁N₃S₂
• Número CAS: 65373-29-7
• Peso molecular: 237.34
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD01018163
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [s]1c(nnc1NC)SCc2ccccc2
• InChI: 1S/C10H11N3S2/c1-11-9-12-13-10(15-9)14-7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,11,12)
• InChI key: KFLNRVSOQJTXDG-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

GPR171 antagonist

MS0021570 is a potent antagonist of GPR171, a G protein-coupled receptor of BigLEN (b-LEN), which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable