SML1097

BC8-15

≥98% (HPLC)

• Sinónimos: 3-[(3-Ethyl-1,2,4-triazolo[4,3-c]quinazolin-5-yl)amino]-benzoic acid
• Fórmula empírica (notación de Hill): C₁₈H₁₅N₅O₂
• Número CAS: 950385-77-0
• Peso molecular: 333.34
• UNSPSC Code: 41106305
• PubChem Substance ID: 329825474
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CCC1=NN=C2N1C(NC3=CC=CC(C(O)=O)=C3)=NC4=CC=CC=C42
• InChI: 1S/C18H15N5O2/c1-2-15-21-22-16-13-8-3-4-9-14(13)20-18(23(15)16)19-12-7-5-6-11(10-12)17(24)25/h3-10H,2H2,1H3,(H,19,20)(H,24,25)
• InChI key: INDKHRIZOIEPIG-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

BC8-15 is a potent PDE4/8 inhibitor that elevates steroidogenesis in mouse Leydig cells.

BC8-15 is a potent PDE4/8 inhibitor.

BC8-15 has the ability to block PDE8A (phosphodiesterase 8A) and PDE4A (phosphodiesterase 4A) with IC50 values of 280 and 220 nM. It helps to increase the synthesis of the steroid from both primary Leydig cells and MA-10 cells.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable