SML1006

EGA

≥98% (HPLC)

• Sinónimos: 2-[(4-Bromophenyl)methylene]-N-(2,6-dimethylphenyl)-hydrazinecarboxamide
• Fórmula empírica (notación de Hill): C₁₆H₁₆BrN₃O
• Número CAS: 415687-81-9
• Peso molecular: 346.22
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/vial, clear (warmed)
• storage temp.: 2-8°C

Descripción

Biochem/physiol Actions

EGA is a small molecule that blocks the entry of anthrax lethal toxin by inhibiting trafficking pathways in acidified endosomes, without affecting endosome pH. EGA blocks trafficking of other toxins, including diphtheria toxin, but does not inhibit trafficking of ricin. The compound EGA attenuates lysosomal targeting and degradation of the EGF receptor, but does not block does not block endosomal recycling of transferrin.

EGA is an inhiitor of endosomal trafficking.

Features and Benefits

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Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable