SML0246

Tirofiban hydrochloride monohydrate

≥98% (HPLC)

• Sinónimos: L 700462, MK 383, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
• Fórmula empírica (notación de Hill): C₂₂H₃₆N₂O₅S·HCl·H₂O
• Número CAS: 150915-40-5
• Peso molecular: 495.07
• NACRES: NA.77
• PubChem Substance ID: 329825256
• UNSPSC Code: 12352200
• MDL number: MFCD07368623
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -10 to -18° (c=1, MeOH)
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: >12 mg/mL at warmed to 60 °C
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: OC([C@@H](NS(CCCC)(=O)=O)CC1=CC=C(C=C1)OCCCCC2CCNCC2)=O.Cl.O
• InChI: 1S/C22H36N2O5S.ClH.H2O/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18;;/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26);1H;1H2/t21-;;/m0../s1
• InChI key: HWAAPJPFZPHHBC-FGJQBABTSA-N
• Gene Information: human ... ITGA2B(3674), ITGB3(3690)

Descripción

Application

Tirofiban hydrochloride monohydrate has been used as an αIIbβ3 integrin (glycoprotein IIb/IIIa) inhibitor for mouse induced pluripotent stem cell (iPSC) culture.

Biochem/physiol Actions

Tirofiban hydrochloride is a potent non-peptide, glycoprotein IIb/IIIa inhibitor. Blocks platelet aggregation and thrombus formation.

Tirofiban hydrochloride monohydrate is an αIIbβIII integrin inhibitor and an anticoagulant

Tirofiban might cause thrombocytopenia.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable