SML0060

NB001

≥98% (HPLC)

• Sinónimos: 5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanol; HTS 09836
• Fórmula empírica (notación de Hill): C₁₂H₂₀N₆O
• Número CAS: 686301-48-4
• Peso molecular: 264.33
• NACRES: NA.77
• PubChem Substance ID: 329825126
• UNSPSC Code: 41106305
• MDL number: MFCD03086724
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: H₂O: ≥24 mg/mL
• storage temp.: −20°C
• SMILES string: Nc1ncnc2n(CCNCCCCCO)cnc12
• InChI: 1S/C12H20N6O/c13-11-10-12(16-8-15-11)18(9-17-10)6-5-14-4-2-1-3-7-19/h8-9,14,19H,1-7H2,(H2,13,15,16)
• InChI key: CVPTTZZCRDVGSU-UHFFFAOYSA-N

Descripción

Application

NB001 may be used in adenylyl cyclase 1-mediated cell signaling studies.

Biochem/physiol Actions

NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. NB001 may reduce cAMP accumulation in cells through an unknown mechanism that is dependent on AC1.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable