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S9896

Sigma-Aldrich

Saporin Peptide

lyophilized powder, from Saponaria officinalis seeds

Sinónimos:

Saponin Extract

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About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.32

Nombre del producto

Saporin from Saponaria officinalis seeds, lyophilized powder

origen biológico

plant seeds (Saponaria officinalis)

Nivel de calidad

Ensayo

10.00-30.00%

Formulario

lyophilized powder

composición

Protein, ~20% Lowry

técnicas

activity assay: suitable

temp. de almacenamiento

2-8°C

Descripción general

Saporin from Saponaria officinalis seeds has an N-terminal domain which is β-stranded and a C-terminal domain which is α-helical. It is made up of 253 amino acids and has a molecular weight of 28,621Da.

Aplicación

Saporin from Saponaria officinalis seeds has been used to study its antifungal activity against Fusarium verticillioides.

Acciones bioquímicas o fisiológicas

Saporin from Saponaria officinalis seeds is a ribosome inactivating protein. It is used for the preparation of immunoconjugates. It has been shown to induce the formation of micronuclei in cultured human lymphocytes, thereby reducing cell viability and enhancing apoptosis.

Envase

Package size based on protein content.

Forma física

Lyophilized powder containing glucose and sodium phosphate buffer salts

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Visite la Librería de documentos

Elizabeth S Ingham et al.
The Journal of comparative neurology, 516(2), 125-140 (2009-07-04)
In mammals, non-image-forming visual functions, including circadian photoentrainment and the pupillary light reflex, are thought to be mediated by the combination of rods, cones, and the melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs). Although several genetic models have been developed
R Iglesias et al.
FEBS letters, 325(3), 291-294 (1993-07-05)
The type 1 ribosome-inactivating protein (RIP) saporin 5 isolated from seeds of Saponaria officinalis L. strongly inhibited translation carried out by Vicia sativa L. purified ribosomes. The toxin multidepurinated V. sativa rRNA, which upon treatment with acid aniline releases several
The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome.
Savino C
Febs Letters, 470(3), 239-243 (2000)
A P Fordham-Skelton et al.
Molecular & general genetics : MGG, 229(3), 460-466 (1991-10-01)
A. Saponaria (soapwort) genomic library was screened with a PCR-derived saporin-specific gene probe. The nucleotide sequences of three saporin genomic clones were determined. One of the clones contained a full-length saporin coding sequence whilst the other two were truncated. A
The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds.
Maras B
Biochemistry International, 21(5), 831-838 (1990)

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