S5261

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

• Sinónimos: Selenious acid, Sodium salt
• Fórmula lineal: Na₂SeO₃
• Número CAS: 10102-18-8
• Peso molecular: 172.94
• NACRES: NA.75
• PubChem Substance ID: 24899643
• UNSPSC Code: 12352205
• EC Number: 233-267-9
• MDL number: MFCD00003489

Propiedades

• biological source: synthetic (inorganic)
• Quality Segment: 200
• product line: BioReagent
• assay: ≥98%
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: >350 °C (lit.)
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• SMILES string: [Na+].[Na+].[O-][Se]([O-])=O
• InChI: 1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
• InChI key: BVTBRVFYZUCAKH-UHFFFAOYSA-L

Descripción

Application

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Información de seguridad

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H300 + H330,H315,H317,H319,H411
• pcodes: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• supp_hazards: EUH031
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges