RAB0543

Human IL18 / Interleukin-18 ELISA Kit

for serum, plasma, cell culture supernatants and urine

• Sinónimos: IFN-gamma-inducing factor, IL-18, Interleukin-18
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... IL18(3606)
• Input: sample type cell culture supernatant(s); sample type urine; sample type plasma; sample type serum
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Propiedades

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type urine; sample type plasma; sample type serum
• assay range: inter-assay cv: <10%; intra-assay cv: <12%; sensitivity: 0.5 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL18(3606)

Descripción

General description

The antibody pair provided in this kit detects Human IL-18 in serum, plasma, cell culture supernatants, and urine. Interleukin-18 (IL-18) is a proinflammatory cytokine, expressed in most of the mammalian tissues including adipose, liver and skeletal muscle. It is generated as pro-IL-18 which undergoes cleavage to form a mature IL-18 possessing the signal peptide. IL-18 induces Th1 (T helper cell 1) lymphocyte action mediated by interferon-γ. It controls the metabolism of lipids and glucose. Inflammasome activation is responsible for IL-18 release, which is a significant event in response to viral infection. Increased level of IL-18 is observed in kidney and liver disease, diabetes, atherosclerosis, autoimmune disease such as rheumatoid arthritis and asthma. It is also associated with the development of renal dysfunction.

Application

Human IL18 / Interleukin-18 ELISA Kit has been used to evaluate the macrophage cytokines production in response to trans-stilbene and terphenyl compounds. It has also been used to analyze and measure IL-18 levels in the urine of chronic kidney disease patients.

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

• RABTMB3

  ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  SDS
• RABSTOP3

  ELISA Stop Solution (Item I)

  SDS
• RABELADB

  ELISA 5X Assay/Sample Diluent Buffer B (Item E1)

  SDS
• RABELADA

  ELISA 1X Assay/Sample Diluent Buffer A (Item D1)

  SDS
• RABWASH4

  20X Wash Buffer (Item B)

  SDS

Información de seguridad

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Clase de almacenamiento: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable