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PLA0001

Sigma-Aldrich

Rabbit anti-c-myc Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Sinónimos:

MRTL, MYCC, avian myelocytomatosis viral oncogene homolog, bHLHe39, c-Myc, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc myelocytomatosis viral oncogene homolog

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

ELISA: 1:1,000- 1:30,000
ELISA: 1:100- 1:500 (for coating plates)
immunocytochemistry: 1:100-1:400
immunoprecipitation (IP): 1- 4 μg/mg
western blot: 1:1,000- 1:30,000

accession no.

NP_002458.2

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... c-myc(4609)

Immunogen

Rabbits were immunized with a synthetic peptide representing amino acid residues 410—419 (EQKLISEEDL) of human myc conjugated to KLH. Antibody was isolated by affinity chromatography using the peptide immobilized on solid support.

Physical form

Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide

Other Notes

The c-myc epitope tag is a commonly used epitope tag engineered onto the N- or C- terminus of a protein of interest so that the tagged protein can be analyzed and visualized using immunochemical methods. The recognized c-myc epitope represents amino acid residues 410-419, EQKLISEEDL, of human c-myc.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cancers, 12(7) (2020-07-16)
U2AF65 (U2AF2) and PUF60 (PUF60) are splicing factors important for recruitment of the U2 small nuclear ribonucleoprotein to lariat branch points and selection of 3' splice sites (3'ss). Both proteins preferentially bind uridine-rich sequences upstream of 3'ss via their RNA
Charles Campbell et al.
Journal of cell science, 129(20), 3832-3844 (2016-09-17)
Sonic Hedgehog (Shh) is a secreted morphogen that is an essential regulator of patterning and growth. The Shh full-length protein undergoes autocleavage in the endoplasmic reticulum to generate the biologically active N-terminal fragment (ShhN), which is destined for secretion. We
Shuo Yang et al.
Developmental biology, 495, 35-41 (2022-12-18)
Cell fate specification is essential for every major event of embryogenesis, and subsequent cell maturation ensures individual cell types acquire specialized functions. The mechanisms that regulate cell fate specification have been studied exhaustively, and each technological advance in developmental biology
Javier Vázquez-Marín et al.
Development (Cambridge, England), 146(13) (2019-05-31)
Yap1/Taz are well-known Hippo effectors triggering complex transcriptional programs controlling growth, survival and cancer progression. Here, we describe yap1b, a new Yap1/Taz family member with a unique transcriptional activation domain that cannot be phosphorylated by Src/Yes kinases. We show that
Reuben J Pengelly et al.
Nucleic acids research, 50(10), 5493-5512 (2022-04-28)
Auxilliary splicing sequences in exons, known as enhancers (ESEs) and silencers (ESSs), have been subject to strong selection pressures at the RNA and protein level. The protein component of this splicing code is substantial, recently estimated at ∼50% of the
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