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O8010

Sigma-Aldrich

Okadaic acid ammonium salt from Prorocentrum concavum

≥90% (HPLC), solid

Sinónimos:

OA

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About This Item

Fórmula empírica (notación de Hill):
C44H68O13 · NH3
Número de CAS:
155716-06-6
Peso molecular:
822.03
Número MDL:
MFCD00153856
Código UNSPSC:
12352106
ID de la sustancia en PubChem:
24898053
NACRES:
NA.77

origen biológico

plant (Prorocentrum concavum)

Nivel de calidad

200

Ensayo

≥90% (HPLC)

Formulario

solid

color

white

solubilidad

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

temp. de almacenamiento

−20°C

cadena SMILES

[H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O

InChI

1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

Clave InChI

ZBOMSHVRJSJGNR-JBNKPAQWSA-N

Acciones bioquímicas o fisiológicas

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301 + H311 + H331,H315

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number
SLCN4651
SLCF6121
SLCD0695
SLCC9868
SLBZ9425

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Sigma-Aldrich

208851

Calyculin A, Discodermia calyx

PTX-11 solution 20 μg/g in methanol (nominal concentration), certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

80099

PTX-11 solution

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