N0186

Nourseothricin sulfate

powder, suitable for cell culture, BioReagent

• Sinónimos: ClonNAT, NTC
• UNSPSC Code: 12352207
• NACRES: NA.76

Propiedades

• Nombre del producto: Nourseothricin sulfate, suitable for cell culture
• biological source: Streptomyces sp.
• Quality Segment: 200
• form: powder
• storage temp.: 2-8°C

Descripción

General description

Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.

Application

Nourseothricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

Biochem/physiol Actions

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.

Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

Packaging

10mg, 50mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable