L2777

Lisinopril

ACE Inhibitor

• Sinónimos: (S)-Nα-(1-Carboxy-3-phenylpropyl)-Lys-Pro
• UNSPSC Code: 12352204
• EC Number: 278-488-1
• NACRES: NA.26

Propiedades

• Quality Segment: 200

Descripción

General description

Lisinopril is a nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor. It is used in the treatment of heart failure and hypertension. Lisinopril is an antihypertensive and anticongestive agent, like other members of its family. It is water-soluble and possesses weak chelating properties.

Application

Lisinopril has been used as an angiotensin-converting enzyme (ACE) inhibitor:

• in combination with spironolactone, to study their effects on cardiac and skeletal muscles in the Duchenne muscular dystrophy (DMD) mice model
• standard in in vitro ACE inhibitory assay
• as a negative control in ACE enzymatic assay

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H360D,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1A - STOT RE 2
• target_organs: Kidney
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)