K1750

α-Ketoglutaric acid

≥98.5% (NaOH, titration)

• Sinónimos: 2-Oxoglutaric acid, 2-Oxopentanedioic acid
• Fórmula lineal: HOOCCH₂CH₂COCOOH
• Número CAS: 328-50-7
• Peso molecular: 146.10
• UNSPSC Code: 12352204
• NACRES: NA.32
• PubChem Substance ID: 57654314
• EC Number: 206-330-3
• Beilstein/REAXYS Number: 1705689
• MDL number: MFCD00004165

Propiedades

• Quality Segment: 200
• assay: ≥98.5% (NaOH, titration)
• form: powder
• solubility: water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: OC(=O)CCC(=O)C(O)=O
• InChI: 1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
• InChI key: KPGXRSRHYNQIFN-UHFFFAOYSA-N

Descripción

General description

α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle.

Application

α-Ketoglutaric acid (α-KG) has been used:

• to study its effects on swine fecal microflora in an in vitro fermentation system
• to study its effects on the activation of CD8⁺ T-cells
• as a substrate in glutamate oxaloacetate transaminase (GOT2) mitochondrial lysate assay

Biochem/physiol Actions

α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries.

Información de seguridad

• Pictogramas: GHS05
• Palabra de advertencia: Danger
• Códigos de peligro: H318
• Indicaciones de precaución: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): dust mask type N95 (US), Eyeshields, Gloves