Saltar al contenido
Merck
Todas las fotos(1)

Documentos

E1378

Sigma-Aldrich

Escin

≥95%, powder

Sinónimos:

Aescin

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Número de CAS:
6805-41-0
EC Number:
229-880-6
MDL number:
MFCD00076054
UNSPSC Code:
12352201
PubChem Substance ID:
24894403
NACRES:
NA.25

biological source

plant (Aesculus chinensis)

Quality Level

200

assay

≥95%

form

powder

impurities

≤6.0% Water (Karl Fischer)

color

white

solubility

methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

C\C=C(/C)C(=O)OC1[C@H](OC(C)=O)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(O)=O)[C@](C)(CO)C5CCC34C)C2CC1(C)C

InChI

1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43?,44+,47+,48-,49-,51?,52-,53?,54-,55?/m1/s1

InChI key

AXNVHPCVMSNXNP-YSYFQUGBSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Escin, a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, is used and studied as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. It may be used to study its pharmacokinetics, safety and efficacy as a chemosensitizer and modulator of NF-κ B cell signaling.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 8

1 of 8

Sigma-Aldrich

Sigma-Aldrich

5.30918

PTC-124

AMMONIUM GLYCYRRHIZINATE AldrichCPR

S641529

AMMONIUM GLYCYRRHIZINATE

Arbutin ≥98% (HPLC)

Sigma-Aldrich

A4256

Arbutin

α-Hederin primary reference standard

01240585

α-Hederin

1,4-Cineole analytical standard

Supelco

27393

1,4-Cineole

Esculin European Pharmacopoeia (EP) Reference Standard

Y0001612

Esculin

Soyasaponin I

Sigma-Aldrich

S9951

Soyasaponin I

Hederacoside C primary reference standard

00930585

Hederacoside C

Wenyu Xin et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(4), 272-277 (2010-09-21)
Escin, a natural mixture of triterpenoid saponins isolated from the seed of the horse chestnut (Aesculus hippocastanum), had been demonstrated to possess anti-edematous and anti-inflammatory effects. The present study was designed to investigate whether escin exhibits synergistic anti-inflammatory effects when
Hang Zhao et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 54(3), 201-207 (2007-03-03)
The purpose of this study was to determine if intrathecal landiolol, a beta1-blocker, can modulate formalin-induced nociception and spinal c-Fos expression in mice, in the absence of anesthesia. Thirty-two mice were randomly assigned to one of four groups: the control
Kuzhuvelil B Harikumar et al.
Molecular pharmacology, 77(5), 818-827 (2010-01-28)
Agents that can enhance tumor cell apoptosis and inhibit invasion have potential for the treatment of cancer. Here, we report the identification of escin, a pentacyclic triterpenoid from horse chestnut that exhibits antitumor potential against leukemia and multiple myeloma. Whether
Xiu-Jun Wu et al.
Journal of ethnopharmacology, 151(2), 839-845 (2013-12-18)
Adequate pharmacokinetic data of escin, a natural mixture of triterpene saponins used for the treatment of chronic venous insufficiency, hemorrhoids, inflammation and edema, is of special interest in view of the growing use of escin agent in clinical medicine. However
J S Fan et al.
Pflugers Archiv : European journal of physiology, 436(6), 1021-1023 (1998-11-03)
Perforated patch recording with nystatin, amphotericin B and gramicidin can be more difficult in the hands of some investigators than others. In addition, it is difficult to introduce low molecular weight substances such as dyes into the cytoplasm in such
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico