E1378

Escin

≥95%, powder

• Sinónimos: Aescin
• Número CAS: 6805-41-0
• NACRES: NA.25
• PubChem Substance ID: 24894403
• UNSPSC Code: 12352201
• EC Number: 229-880-6
• MDL number: MFCD00076054

Propiedades

• biological source: plant (Aesculus chinensis)
• Quality Segment: 200
• assay: ≥95%
• form: powder
• impurities: ≤6.0% Water (Karl Fischer)
• color: white
• solubility: methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• SMILES string: C\C=C(/C)C(=O)OC1[C@H](OC(C)=O)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(O)=O)[C@](C)(CO)C5CCC34C)C2CC1(C)C
• InChI: 1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43?,44+,47+,48-,49-,51?,52-,53?,54-,55?/m1/s1
• InChI key: AXNVHPCVMSNXNP-YSYFQUGBSA-N

Descripción

Application

Escin, a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, is used and studied as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. It may be used to study its pharmacokinetics, safety and efficacy as a chemosensitizer and modulator of NF-κ B cell signaling.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H332
• pcodes: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Gloves