C0625

Caffeic acid

≥98.0% (HPLC)

• Sinónimos: 3,4-Dihydroxybenzeneacrylic acid, 3,4-Dihydroxycinnamic acid, 3-(3,4-Dihydroxyphenyl)-2-propenoic acid
• Fórmula lineal: (HO)₂C₆H₃CH=CHCO₂H
• Número de CAS: 331-39-5
• Peso molecular: 180.16
• Beilstein: 1954563
• Número CE: 206-361-2
• Número MDL: MFCD00004392
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 24278290
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98.0% (HPLC)
• Formulario: powder
• mp: 211-213 °C (dec.) (lit.)
• solubilidad: ethanol: 50 mg/mL
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• cadena SMILES: OC(=O)\C=C\c1ccc(O)c(O)c1
• InChI: 1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
• Clave InChI: QAIPRVGONGVQAS-DUXPYHPUSA-N
• Información sobre el gen: human ... ELA2(1991) ; rat ... Alox5(25290)

Descripción

Descripción general

Caffeic acid exists in its free and ester form. It is considered as the predominant polyphenol, contributing to the hydroxycinnamic acid content in various fruits. Coffee is one of the major source of caffeic acid.[1]

Aplicación

Caffeic acid has been used as a standard of phenolic acid in the study to determine the total phenolic acid content in vegetables after subjecting to alkaline and acid hydrolysis.[2] It has also been used to determine its antioxidant activity by various assay methods.[3]

Acciones bioquímicas o fisiológicas

A natural dietary phenolic compound found in plants that is an anti-oxidant. Inhibits the synthesis of leukotrienes that are involved in immunoregulation, inflammation and allergy. Inhibits Cu²⁺-induced LDL oxidation.

Anti-oxidant phenolic compound found in plants; Inhibits the synthesis of leukotrienes.

Caffeic acid and other polyphenols are metabolized by going through enzyme catalysed methyl transfer, sulfation and glucuronic acid addition.[1] It non-competitively prevents the action of 5-lipoxygenase.[4] Caffeic acid ready undergoes hydrolysis in alkaline conditions.[2]

Características y beneficios

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Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H351
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Carc. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges