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B7166

Sigma-Aldrich

5-Bromouridine 5′-triphosphate sodium salt

≥93%

Sinónimos:

5-BrUTP

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About This Item

Fórmula empírica (notación de Hill):
C9H14BrN2O15P3 · xNa+
Número de CAS:
161848-60-8
Peso molecular:
563.04 (free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
24891977
NACRES:
NA.51

biological source

synthetic (organic)

assay

≥93%

form

powder

storage temp.

−20°C

SMILES string

OP(OP(OP(O)(O)=O)(O)=O)(OC[C@H]1O[C@@H](N(C=C2Br)C(NC2=O)=O)[C@H](O)[C@@H]1O)=O.[Na]

InChI

1S/3Na/q3*+1

InChI key

BVPYARCRLTXGBD-UHFFFAOYSA-N

General description

5-Bromouridine 5′-triphosphate (5-BrUTP) is used to measure transcription via labeling of ribonucleic acids (RNA). RNA or cells labeled via 5-BrUTP incorporation may be detected immunologically with antibodies.

Application

5-Bromouridine 5′-triphosphate (5-BrUTP) is used to measure transcription via labeling of ribonucleic acids (RNA). RNA or cells labeled via 5-BrUTP incorporation may be detected immunologically with antibodies.
5-Bromouridine 5′-triphosphate sodium salt has been used:
  • to infer the chromosome intermingling between embryonic stem (ES) cells (differentiated and undifferentiated) and terminally differentiated NIH3T3 cells
  • to label nascent RNA in in vivo transcription analysis using fibroblasts
  • and transfected MDA-MB-231 cells
  • to label RNA for nuclear run-on experiments

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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