Saltar al contenido
Merck
Todas las fotos(4)

Documentos

B0385

Sigma-Aldrich

Beclomethasone

≥99%

Sinónimos:

9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(4)

About This Item

Fórmula empírica (notación de Hill):
C22H29ClO5
Número de CAS:
4419-39-0
Peso molecular:
408.92
EC Number:
224-585-9
MDL number:
MFCD00135614
UNSPSC Code:
12352200
PubChem Substance ID:
24278253
NACRES:
NA.77

assay

≥99%

form

powder

originator

GlaxoSmithKline

storage temp.

2-8°C

SMILES string

[H][C@]12C[C@@H](C)[C@@](O)(C(=O)CO)[C@]1(C)C[C@@H](O)[C@@]3(Cl)[C@]2([H])CCC4=CC(=O)C=C[C@@]34C

InChI

1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12?,15?,16?,17?,19?,20?,21-,22?/m0/s1

InChI key

NBMKJKDGKREAPL-WOOYFSPWSA-N

Gene Information

human ... CYP1A2(1544)

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Beclomethasone has been used in MS−MS (mass spectrometry) methods for the analysis of β-agonists, corticosteroids, chloramphenicol and penicillins. It has also been used to find the differential response of glucocorticoids in larval regeneration model.

Biochem/physiol Actions

Beclomethasone is an anti-inflammatory glucocorticoid.
It helps to decrease airway hyperresponsiveness. It also helps to regulate symptoms of asthma.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Lydia J Finney et al.
The Journal of allergy and clinical immunology, 147(2), 510-519 (2020-10-18)
The mechanisms underlying altered susceptibility and propensity to severe Coronavirus disease 2019 (COVID-19) disease in at-risk groups such as patients with chronic obstructive pulmonary disease (COPD) are poorly understood. Inhaled corticosteroids (ICSs) are widely used in COPD, but the extent
Yufei Xie et al.
Disease models & mechanisms, 12(5) (2019-05-11)
Glucocorticoid drugs are widely used to treat immune-related diseases, but their use is limited by side effects and by resistance, which especially occurs in macrophage-dominated diseases. In order to improve glucocorticoid therapies, more research is required into the mechanisms of
A comparative analysis of changes in pMDI drug dose delivery before and after detergent coating using five antistatic valved holding chambers.
Paul Hagedoorn et al.
The journal of allergy and clinical immunology. In practice, 8(3), 1124-1125 (2019-10-09)
A comparison of beclomethasone, salmeterol, and placebo in children with asthma
Simons, FER, et al.
The New England Journal of Medicine, 337(23), 1659-1665 (1997)
Hong Ping Zhang et al.
Allergy and asthma proceedings, 35(4), 278-287 (2014-07-06)
It has proven efficacy in reducing asthma exacerbations, but the effect size of montelukast (a leukotriene receptor antagonist) for varied severity of asthma exacerbations is not systematically assessed. This study was designed to systematically explore the evidence for montelukast, as
Ver todos los artículos relacionados

Artículos

Bioactive Molecules for Immunology Research

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico