No, this product has been tested for in vivo application. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.
30450
Daunorubicin hydrochloride
≥90% (HPLC)
Sinónimos:
Daunomycin hydrochloride
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| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
5 mg | Comprobar disponibilidad del carrito | $191.000 |
25 mg | Comprobar disponibilidad del carrito | $652.000 |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C27H29NO10 · HCl
Número CAS:
Peso molecular:
563.98
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
245-723-4
Beilstein/REAXYS Number:
4229221
MDL number:
Servicio técnico
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Permítanos ayudarlebiological source
synthetic
Quality Segment
assay
≥90% (HPLC)
form
powder
color
red to deep red
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
InChI
1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
InChI key
GUGHGUXZJWAIAS-QQYBVWGSSA-N
Gene Information
human ... TOP2A(7153)
General description
Chemical structure: aminoglycoside
Application
Biochem/physiol Actions
On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.
Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.
Packaging
5 mg, 25 mg
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas.
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Este artículo | |||
|---|---|---|---|
| mode of action DNA synthesis | interferes | mode of action - | mode of action - | mode of action DNA synthesis | interferes |
| antibiotic activity spectrum neoplastics | antibiotic activity spectrum - | antibiotic activity spectrum - | antibiotic activity spectrum neoplastics |
| assay ≥90% (HPLC) | assay - | assay - | assay - |
| form powder | form - | form - | form solid |
| biological source synthetic | biological source - | biological source - | biological source - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. - | storage temp. 2-8°C |
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signalword
Danger
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Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Muta. 2 - Repr. 1B
Clase de almacenamiento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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