A1100000

Ampicillin trihydrate

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: D-(−)-α-Aminobenzylpenicillin
• Fórmula empírica (notación de Hill): C₁₆H₁₉N₃O₄S · 3H₂O
• Número CAS: 7177-48-2
• Peso molecular: 403.45
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329770656
• MDL number: MFCD00072036
• Beilstein/REAXYS Number: 5399534
• eCl@ss: 25140904

Propiedades

• grade: pharmaceutical primary standard
• API family: ampicillin
• manufacturer/tradename: EDQM
• mp: 198-200 °C (dec.) (lit.)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
• InChI: 1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
• InChI key: RXDALBZNGVATNY-CWLIKTDRSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ampicillin trihydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de advertencia: Danger
• Códigos de peligro: H315,H317,H319,H334,H335
• Indicaciones de precaución: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 2
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable