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69899

Monochlorobimane

suitable for fluorescence, ≥70.0% (HPCE)

Sinónimos:

mBCl, Chlorobimane

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A ustedes/SKUDisponibilidadPrecio
5 mg
Comprobar disponibilidad del carrito
$99.000
25 mg
Comprobar disponibilidad del carrito
$311.000
100 mg
Comprobar disponibilidad del carrito
$1.030.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C10H11ClN2O2
Número CAS:
Peso molecular:
226.66
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4440901
Assay:
≥70.0% (HPCE)
Form:
powder

$99.000


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Quality Segment

assay

≥70.0% (HPCE)

form

powder

mp

135-136 °C (lit.)

solubility

DMF: soluble, DMSO: soluble, acetonitrile: soluble, methanol: soluble

fluorescence

λex 380 nm; λem 461 nm in methanol, λex 390 nm; λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione)

suitability

suitable for fluorescence

SMILES string

CC1=C(C)C(=O)N2N1C(CCl)=C(C)C2=O

InChI

1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChI key

SUIPVTCEECPFIB-UHFFFAOYSA-N

General description

Monochlorobimane is a glutathione (GSH) fluorescent cell-permeable probe. When incubated with the test cell culture, it readily enters the cells and forms a fluorescent complex. The Monochlorobimane-GSH reaction is catalyzed by glutathione-S-transferase, which is detected fluorometrically.

Monochlorobimane, also known as mBCl, is a non-fluorescent compound that forms a fluorescent complex upon reaction. The fluorescence is detected at 394/490nm.

Application

Monochlorobimane is used as a fluorescent agent in fluorometric glutathione assays. It is used to detect the principal intracellular low-molecular-weight thiols, which play a pivotal role in the defense mechanism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Este artículo
698982188421879
assay

≥70.0% (HPCE)

assay

≥95% (HPCE)

assay

≥85% (HPCE)

assay

≥90.0% (HPLC)

form

powder

form

solid

form

-

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMF: soluble, acetonitrile: soluble, DMSO: soluble, methanol: soluble

solubility

DMF: soluble, DMSO: soluble, acetonitrile: soluble, methanol: soluble

solubility

DMF: soluble, DMSO: soluble, methanol: soluble

solubility

DMSO: soluble

suitability

suitable for fluorescence

suitability

suitable for fluorescence

suitability

suitable for fluorescence

suitability

suitable for fluorescence

fluorescence

λex 380 nm; λem 461 nm in methanol, λex 390 nm; λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione)

fluorescence

λex 390 nm; λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione), λex 398 nm

fluorescence

λex 470 nm; λem 529 nm in 0.1 M Tris pH 8.0 (esterase)

fluorescence

λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0 (esterase)


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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