347436

GGACK

≥80% (HPLC), Urokinase inhibitor, solid

• Sinónimos: GGACK, Glu-Gly-Arg-chloromethyl Ketone
• Fórmula empírica (notación de Hill): C₁₄H₂₅ClN₆O₅
• Peso molecular: 392.84
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥80% (HPLC)
• Form: solid
• Storage condition: OK to freeze, desiccated (hygroscopic)

Propiedades

• Nombre del producto: GGACK, An irreversible inhibitor of urokinase (IC₅₀ 1 µM) and Factor Xa.
• Quality Segment: 100
• assay: ≥80% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• color: white
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

An irreversible inhibitor of urokinase (IC₅₀<1 µM) and Factor Xa.

Biochem/physiol Actions

Cell permeable: no

Primary Target
urokinase

Product does not compete with ATP.

Reversible: no

Target IC₅₀: <1 µM against urokinase

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Avoid freeze/thaw cycles of stock solution.

Other Notes

H-Glu-Gly-Arg-CMK

Kettner, C., and Shaw, E. 1979. Biochim. Biophys. Acta569, 31.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 1
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable