14-725-M

EGFR (T790M) Protein, active, 10 µg

Active, N-terminal GST-tagged recombinant human EGF Receptor, amino acids 696end containing the mutation T790M, for use in Enzyme Assays.

• UNSPSC Code: 12352202
• NACRES: NA.32
• eCl@ss: 32160405
• Biological source: human
• Recombinant: expressed in baculovirus infected Sf21 cells
• Mol wt: M_w 86 kDa

Propiedades

• biological source: human
• Quality Segment: 100, 300
• recombinant: expressed in baculovirus infected Sf21 cells
• mol wt: M_w 86 kDa
• manufacturer/tradename: Upstate^®
• technique(s): activity assay: suitable
• NCBI accession no.: NM_005228.3, NM_201282.1, NM_201283.1, NM_201284.1
• UniProt accession no.: P00533

Descripción

General description

N-terminal GST-tagged recombinant human EGF Receptor, amino acids 696end containing the mutation T790M

Product Source: expressed by baculovirus in Sf21 cells

Application

Research Category
Metabolism

Inflammation & Immunology

Research Sub Category
Obesity

Metabolic Disorders

Osteoporosis

Arthritis

Biochem/physiol Actions

Protein Target: EGFR

Target Sub-Family: TK

Physical form

Glutathione-agarose

Preparation Note

6 months at -70°C from date of shipment

Analysis Note

routinely evaluated by phosphorylation of 250μM substrate peptide (GGMEDIYFEFMGGKKK)

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Clase de almacenamiento: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable