1.04967

Potassium cyanide

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Sinónimos: Potassium cyanide, Cyanogen potassium
• Fórmula lineal: KCN
• Número CAS: 151-50-8
• Peso molecular: 65.12
• UNSPSC Code: 12352302
• EC Index Number: 205-792-3
• NACRES: NA.21
• MDL number: MFCD00011397
• Assay: ≥97% (silver nitrate titration)
• Grade: ACS reagent
• Form: solid

Propiedades

• grade: ACS reagent
• Quality Segment: 300
• agency: reag. ISO, reag. Ph. Eur.
• product line: EMSURE^®
• assay: ≥97% (silver nitrate titration)
• form: solid
• potency: 7.49 mg/kg LD₅₀, oral (Rat), 14.29 mg/kg LD₅₀, skin (Rabbit)
• pH: 11-12 (20 °C, 20 g/L in H₂O)
• bp: 1625 °C/1013 hPa
• mp: 634 °C
• density: 1.55 g/cm³ at 20 °C
• bulk density: 750 kg/m³
• anion traces: chloride (Cl^-): ≤0.02%, phosphate (PO₄^3-): ≤0.005%, sulfate (SO₄^2-): ≤0.01%, sulfide (S^2-): ≤0.0005%, thiocyanate (SCN^-): ≤0.01%
• cation traces: Fe: ≤0.01%, Na: ≤0.5%, Pb: ≤0.0002%
• storage temp.: no temp limit
• SMILES string: [K+].N#[C-]
• InChI: 1S/CN.K/c1-2;/q-1;+1
• InChI key: NNFCIKHAZHQZJG-UHFFFAOYSA-N

Descripción

Application

• Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.: The research identifies iminium intermediates in the metabolism of tepotinib using liquid chromatography-mass spectrometry. Potassium cyanide is utilized to trap reactive intermediates, providing insights into drug metabolism pathways (Abdelhameed et al., 2020).


• Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.: This paper describes the synthesis of stable-isotope-labeled compounds using potassium cyanide in the synthesis process to understand the chemical structure and reactivity of these labeled compounds (Cao et al., 2020).


• Carbon-13 synthesis and NMR spectroscopic geometric isomer evaluation to support the filing of teriflunomide.: The study involves the synthesis of carbon-13 labeled teriflunomide and its isomers, using potassium cyanide in the synthetic pathway. The NMR spectroscopic analysis helped in the evaluation of geometric isomers (Kurz et al., 2021).


• A hybrid lipid membrane coating "shape-locks" silver nanoparticles to prevent surface oxidation and silver ion dissolution.: This research develops a hybrid lipid membrane to stabilize silver nanoparticles, using potassium cyanide in the analytical phase to measure the prevention of silver ion dissolution and oxidation (Miesen et al., 2020).

Analysis Note

Assay (argentometric): ≥ 97.0 %
Chloride (Cl): ≤ 0.02 %
Phosphate (PO₄): ≤ 0.005 %
Sulfate (SO₄): ≤ 0.01 %
Sulphide (S): ≤ 0.0005 %
Thiocyanate (SCN): ≤ 0.01 %
Fe (Iron): ≤ 0.01 %
Na (Sodium): ≤ 0.5 %
Pb (Lead): ≤ 0.0002 %
Corresponds to ACS,Reag. Ph Eur

Other Notes

Replaces: PX1435; PX1435-5; PX1435-1; PX1435-20

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06,GHS08,GHS05,GHS09
• Palabra de advertencia: Danger
• Códigos de peligro: H290,H300 + H310 + H330,H372,H410
• Órganos diana: Thyroid
• supp_hazards: EUH032
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• Indicaciones de precaución: P260 - P262 - P264 - P280 - P301 + P310 + P330 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1
• Clase de almacenamiento: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials