1.02572

Schiff′s reagent Intense

for the detection of aldehyde and mucosubstances in microscopy

• NACRES: NA.41
• UNSPSC Code: 41116130

Propiedades

• Quality Segment: 400
• form: liquid
• IVD: for in vitro diagnostic use
• pH: 1.74 ( in H₂O)
• density: 1.014 g/cm³ at 20 °C
• storage temp.: 20-25°C

Descripción

General description

The Schiff′s reagent Intense - for the detection of aldehyde and mucosubstances in microscopy, is a ready-to-use solution used for human-medical cell diagnosis and serves the histological investigation of sample material of human origin, for example histological sections of e. g. the intestine or liver. This ready-to-use Schiff′s reagent Intense can be used to stain mucopolysaccharides in histological tissue specimens. The PAS (periodic acid schiff) reaction is one of the most frequently used chemical methods for the detection of aldehyde and mucosubstances in microscopy. In the PAS reaction, the histological specimen material is first treated with periodic acid, resulting in the oxidation of the 1,2-glycols into aldehyde groups. The addition of Schiff′s reagent (fuchsin-sulfuric acid) in the second step causes the aldehydes to react to form a brilliant red color. In the end result, the PAS reaction yields a specific color reaction with unsubstituted polysaccharides, neutral mucopolysaccharides, muco- and glycoproteins, and glyco- and phospholipids.
The PAS reaction can be further combined with the Alcian blue staining method to detect mucosubstances (glycosaminoglycans).
The 500 ml bottle is sufficient for 3000 stainings. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Application

For the detection of aldehydes, polysaccharides (glycogen), and mucosubstances (glycoproteins, glycolipids, mucins)

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H319
• Indicaciones de precaución: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Clase de almacenamiento: 12 - Non Combustible Liquids
• ¿Qué está pasando?: WGK 2
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable