07-228

Anti-TACC2 Antibody

Upstate^®, from rabbit

• Sinónimos: transforming, acidic coiled-coil containing protein 2
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 20

Propiedades

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, mouse
• species reactivity (predicted by homology): rat (based on 100% sequence homology)
• manufacturer/tradename: Upstate^®
• technique(s): western blot: suitable
• NCBI accession no.: NP_996738
• UniProt accession no.: Q9JJG0
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TACC2(10579)

Descripción

General description

Observed molecular weight, 73 kDa
Note this protein can be highly modified and several isoforms exist.

TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009).

Immunogen

KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2.

Application

Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB.

Analysis Note

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Clase de almacenamiento: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable