F6889
Famotidine
histamine receptor antagonist
Synonym(s):
N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine
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| Size/SKU | Availability | Price |
|---|---|---|
500 mg | Check Cart for Availability | CLP 106,000 |
1 g | Check Cart for Availability | CLP 131,000 |
5 g | Check Cart for Availability | CLP 485,000 |
About This Item
Empirical Formula (Hill Notation):
C8H15N7O2S3
CAS Number:
Molecular Weight:
337.45
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Product Name
Famotidine,
Quality Segment
originator
Johnson & Johnson
SMILES string
N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
InChI
1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
InChI key
XUFQPHANEAPEMJ-UHFFFAOYSA-N
Gene Information
human ... HRH2(3274)
Application
Famotidine has been used to test its effect on the human ether-a-go-go-related gene (hERG) binding transfected in HEK293 membrane. It has also been used in polycaprolactone based drug delivery studies.
Biochem/physiol Actions
H2 histamine receptor antagonist; anti-ulcer agent
Famotidine is not effective on muscarinic and nicotinic receptors. It competitively inhibits the secretion of gastric acid and elicits mucosal injury protection.
Features and Benefits
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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This Item | |||
|---|---|---|---|
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| originator Johnson & Johnson | originator - | originator - | originator - |
| Gene Information human ... HRH2(3274) | Gene Information human ... HRH2(3274) | Gene Information human ... HRH2(3274) | Gene Information human ... HRH2(3274) |
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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