F2929
6-Fluoromevalonate
≥90% (GC), Mevalonate-pyrophosphate decarboxylase inhibitor, viscous liquid
Synonym(s):
Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one, ZR 3516
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | CLP 177,000 |
25 mg | Check Cart for Availability | CLP 669,000 CLP 568,650 |
About This Item
Product Name
6-Fluoromevalonate, ≥90% (GC), viscous liquid
Quality Segment
assay
≥90% (GC)
form
viscous liquid
color
yellow tint
solubility
DMSO: ≥3 mg/mL
storage temp.
2-8°C
SMILES string
OC1(CF)CCOC(=O)C1
InChI
1S/C6H9FO3/c7-4-6(9)1-2-10-5(8)3-6/h9H,1-4H2
InChI key
DPPMVKMESJJAJZ-UHFFFAOYSA-N
Application
- to study the effect of mevalonate pathway inhibition on patient-derived brain tumor-initiating cells (BTICs) growth and self-renewal
- to study its effect on induction of trained immunity by β-glucan in monocytes
- to determine the effect of the mevalonate pathway (MVP) on ADP-ribosylation factor 6 (ARF6) activation
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥90% (GC), viscous liquid | description An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation. | description ≥98% (HPLC), powder or crystals | description United States Pharmacopeia (USP) Reference Standard |
| form viscous liquid | form solid | form powder or crystals | form - |
| assay ≥90% (GC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥3 mg/mL | solubility ethanol: soluble | solubility ethanol: 25-26 mg/mL, clear, colorless | solubility - |
| color yellow tint | color white | color white to light yellow | color - |
Storage Class
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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