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D8946

DMH1

≥98% (HPLC), powder, BMP inhibitor

Synonym(s):

4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline

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Size/SKUAvailabilityPrice
5 mg
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CLP 184,000
25 mg
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CLP 771,000

About This Item

Empirical Formula (Hill Notation):
C24H20N4O
CAS Number:
Molecular Weight:
380.44
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

CLP 184,000


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Product Name

DMH1, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

light yellow to orange

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3

InChI

1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3

InChI key

JMIFGARJSWXZSH-UHFFFAOYSA-N

General description

DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.

Application

DMH1 has been used for bone morphogenetic protein (BMP) inhibition.

Biochem/physiol Actions

DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor.
DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway.

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1 of 1

This Item
203646SML1535475949
description

≥98% (HPLC)

description

The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

description

≥98% (HPLC)

description

The MPS1 Inhibitor, NMS-P715 controls the biological activity of MPS1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

protect from light, OK to freeze

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 16.6 mg/mL

solubility

DMSO: 1 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear, colorless


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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