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Merck

C7013

Coenzyme A–Agarose

Synonym(s):

coa-agarose

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About This Item

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
Technical Service
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form

lyophilized powder

Quality Level

extent of labeling

2-6 μmol per mL gel

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

swelling

1 g swells to 5-10 mL

storage temp.

−20°C

Application

Coenzyme A-agarose is an agarose conjugate, in physical form stabilized with lactose and is used in affinity chromatography, protein chromatography and nucleotide/coenzyme resins. Coenzyme A has been used in studies assessing age-related hearing loss as well as to assess organisms that survive in environments subject to changing oxygen concentrations.

Physical form

Stabilized with lactose


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Daniel L Siehl et al.
The Journal of biological chemistry, 282(15), 11446-11455 (2007-02-03)
GAT is an N-acetyltransferase from Bacillus licheniformis that was optimized by gene shuffling for acetylation of the broad spectrum herbicide, glyphosate, forming the basis of a novel mechanism of glyphosate tolerance in transgenic plants (Castle, L. A., Siehl, D. L.
Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea.
Tanaka, C., et al.
Neurobiology of Aging (2012)
Lawrence M Szewczuk et al.
Biochemistry, 47(39), 10407-10419 (2008-09-06)
Serotonin N-acetyltransferase [arylalkylamine N-acetyltransferase (AANAT)] is a key circadian rhythm enzyme that drives the nocturnal production of melatonin in the pineal. Prior studies have suggested that its light and diurnal regulation involves phosphorylation on key AANAT Ser and Thr residues



Global Trade Item Number

SKUGTIN
C7013-1G04061833511749
C7013-500MG04061833511756