Key Documents

BIS-TRIS

Name: BIS-TRIS
Brand: SIGMA
Price: 68200 CLP

BioXtra, ≥98.0% (titration)

Synonym(s):

2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane

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Size/SKU	Availability	Price
25 g	Check Cart for Availability	CLP 68,200
100 g	Check Cart for Availability	CLP 203,000
500 g	Check Cart for Availability	CLP 757,000

About This Item

Empirical Formula (Hill Notation):

C₈H₁₉NO₅

CAS Number:

6976-37-0

Molecular Weight:

209.24

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24892003

EC Number:

230-237-7

Beilstein/REAXYS Number:

2205275

MDL number:

MFCD00002853

CLP 68,200

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Properties

product line

BioXtra

assay

≥98.0% (titration)

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

9.0-10.1 (20-25 °C, 1 M in H₂O)

useful pH range

5.8-7.2

pKa (25 °C)

6.5

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing

SMILES string

OCCN(CCO)C(CO)(CO)CO

InChI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

InChI key

OWMVSZAMULFTJU-UHFFFAOYSA-N

Description

Application

Optimization of Exosome Isolation: Research on optimizing exosome isolation emphasized the utility of BIS-TRIS in establishing buffer systems that enhance the accuracy of exosome size and morphology analysis, critical for diagnostic applications (Ishii et al., 2023).

Other Notes

Easily compare specifications for BIS-TRIS products with the BIS-TRIS specification table.

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This Item	B9754	B4429	14879
Sigma-Aldrich B7535 BIS-TRIS	Sigma-Aldrich B9754 BIS-TRIS	Sigma-Aldrich B4429 BIS-TRIS	Sigma-Aldrich 14879 BIS-TRIS
assay ≥98.0% (titration)	assay ≥98.0% (titration)	assay ≥98.0%	assay ≥99.0% (NT)
Quality Level 400	Quality Level 400	Quality Level 400	Quality Level 200
product line BioXtra	product line -	product line -	product line BioUltra
form powder	form crystalline powder	form crystalline powder	form powder
application(s) diagnostic assay manufacturing	application(s) advanced drug delivery diagnostic assay manufacturing general analytical microbiology	application(s) diagnostic assay manufacturing	application(s) -
solubility H₂O: 1 M, clear, colorless	solubility H₂O: 500 mg/mL, clear, colorless to very faintly yellow	solubility H₂O: 500 mg/mL, clear, colorless to very faintly yellow	solubility H₂O: 1 M at 20 °C, clear, colorless

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pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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