A3009

4-Androsten-11β-ol-3,17-dione

• Synonym(s): 11β-Hydroxy-4-androstene-3,17-dione
• Empirical Formula (Hill Notation): C₁₉H₂₆O₃
• CAS Number: 382-44-5
• Molecular Weight: 302.41
• MDL number: MFCD00051131
• UNSPSC Code: 51111800
• PubChem Substance ID: 24890715
• NACRES: NA.77

Properties

• Assay: ≥98.00% (TLC)
• Quality Level: 200
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• solubility: chloroform: 49-51 mg/mL, clear, colorless to faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)C(=O)CC[C@@]24[H]
• InChI: 1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
• InChI key: WSCUHXPGYUMQEX-KCZNZURUSA-N

Description

Biochem/physiol Actions

11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves