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112003

Sigma-Aldrich

Hippuric acid

98%

Synonym(s):

N-Benzoylglycine, Benzoylaminoacetic acid

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CLP 79,300
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CLP 94,900
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CLP 245,000

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Estimated to ship onApril 01, 2025


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5 G
CLP 79,300
100 G
CLP 94,900
500 G
CLP 245,000

About This Item

Linear Formula:
C6H5CONHCH2COOH
CAS Number:
Molecular Weight:
179.17
Beilstein:
1073987
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.25

CLP 79,300


Estimated to ship onApril 01, 2025


Request a Bulk Order

Product Name

Hippuric acid, 98%

Quality Level

Assay

98%

form

powder, crystals or chunks

mp

187-191 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)CNC(=O)c1ccccc1

InChI

1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)

InChI key

QIAFMBKCNZACKA-UHFFFAOYSA-N

Gene Information

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Application

Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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H Ukai et al.
Occupational and environmental medicine, 51(8), 523-529 (1994-08-01)
Exposure monitoring by personal diffusive samplers, biological monitoring of toluene exposure by urinary hippuric acid determination, haematology, serum biochemistry for liver function, and a subjective symptom survey by questionnaire were conducted on 303 male solvent workers. They were exposed to
Yoshiharu Itoh et al.
Analytical and bioanalytical chemistry, 403(7), 1841-1850 (2012-03-27)
Cardiovascular disease (CVD) is prevalent in patients with chronic kidney disease (CKD). In hemodialysis (HD) patients, some protein-bound uremic toxins are considered to be associated with CVD. However, it is not yet known which uremic toxins are important in terms
Justin J J van der Hooft et al.
Analytical chemistry, 84(16), 7263-7271 (2012-07-26)
In dietary polyphenol exposure studies, annotation and identification of urinary metabolites present at low (micromolar) concentrations are major obstacles. To determine the biological activity of specific components, it is necessary to have the correct structures and the quantification of the
T Takada et al.
Scientific reports, 8(1), 11147-11147 (2018-07-26)
Chronic kidney disease (CKD) patients accumulate uremic toxins in the body, potentially require dialysis, and can eventually develop cardiovascular disease. CKD incidence has increased worldwide, and preventing CKD progression is one of the most important goals in clinical treatment. In
Kristin J Adolfsen et al.
Nature communications, 12(1), 6215-6215 (2021-10-30)
In phenylketonuria (PKU) patients, a genetic defect in the enzyme phenylalanine hydroxylase (PAH) leads to elevated systemic phenylalanine (Phe), which can result in severe neurological impairment. As a treatment for PKU, Escherichia coli Nissle (EcN) strain SYNB1618 was developed under

Questions

  1. Can this chemical be used in vitro? If so, how to dilute it?

    1 answer
    1. This product has not been tested for in vivo or in vitro applications. Suitability for in vitro use will need to be validated by the end user. Hippuric acid is soluble in water at 3 - 4 mg/mL. Sodium or ammonium hydroxide is suggested for higher concentrations. It may be helpful to view peer-reviewed articles. Please see the publications in the link below:

      https://www.sigmaaldrich.com/search/112003?focus=papers&page=1&perpage=30&sort=relevance&term=112003&type=citation_search

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