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MAB5564

Sigma-Aldrich

Anti-Tubulin β III Antibody

Chemicon®, from mouse

Synonym(s):

Anti-CDCBM, Anti-CDCBM1, Anti-CFEOM3, Anti-CFEOM3A, Anti-FEOM3, Anti-TUBB4, Anti-beta-4

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

Specificity

Beta III Tubulin. This clone is similar to the monoclonal antibody Tuj1.

Application

Anti-Tubulin Antibody, β III detects level of Tubulin & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism
Western blot

Immunohistochemistry: 1:1,000-1:3,000 on neuroblasts in adult rat brain using a fluorescently labeled secondary antibody.

Optimal working dilutions must be determined by end user.

Linkage

Replaces: 04-1049

Physical form

Format: Purified
Liquid in 0.02M phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide..

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner.
Lim, KS; Lim, KJ; Price, AC; Orr, BA; Eberhart, CG; Bar, EE
Oncogene null
Dillon M Voss et al.
Scientific reports, 7(1), 4292-4292 (2017-06-29)
We have previously shown that glioblastoma stem cells (GSCs) are enriched in the hypoxic tumor microenvironment, and that monocarboxylate transporter-4 (MCT4) is critical for mediating GSC signaling in hypoxia. Basigin is involved in many physiological functions during early stages of
Expression and subcellular distribution of imp13 are regulated in brain development.
You, P; Peng, Z; Wang, Y; Tao, T
In Vitro Cellular & Developmental Biology. Animal null
Brian Hitt et al.
The Journal of biological chemistry, 287(46), 38408-38425 (2012-09-19)
BACE1 is the β-secretase enzyme that initiates production of the β-amyloid peptide involved in Alzheimer disease. However, little is known about the functions of BACE1. BACE1-deficient mice exhibit mild but complex neurological phenotypes suggesting therapeutic BACE1 inhibition may not be
Kenneth Hensley et al.
Journal of neuropathology and experimental neurology, 72(10), 955-969 (2013-09-18)
Lanthionine ketimine ([LK] 3,4-dihydro-2H-1,4-thiazine-3,5-dicarboxylic acid) is the archetype for a family of naturally occurring brain sulfur amino acid metabolites, the physiologic function of which is unknown. Lanthionine ketimine and its synthetic derivatives have recently demonstrated neurotrophic, neuroprotective, and antineuroinflammatory properties

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