This product is lyophilized from a solution containing 20 mM Tris-HCl, 2 mM EDTA, pH 7.5. The product may be reconstituted in water. Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
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About This Item
Specific activity:
≥120 units/mg protein
Assay:
≥95% (SDS-PAGE)
Biological source:
human plasma
Pricing and availability is not currently available.
biological source
human plasma
Quality Segment
description
Merck USA index - 14, 7521
assay
≥95% (SDS-PAGE)
form
lyophilized
specific activity
≥120 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: soluble
shipped in
ambient
storage temp.
−20°C
General description
Native plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
Native plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg560.
Physical form
Lyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Irritant (B)
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This Item | |||
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| description - | description - | description - | description Plasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins. |
| biological source human plasma | biological source - | biological source - | biological source human plasma |
| specific activity ≥120 units/mg protein | specific activity - | specific activity - | specific activity - |
| assay ≥95% (SDS-PAGE) | assay - | assay - | assay ≥95% (Clottable proteins) |
| form lyophilized | form liquid | form liquid | form lyophilized |
| storage condition OK to freeze | storage condition OK to freeze, avoid repeated freeze/thaw cycles | storage condition avoid repeated freeze/thaw cycles, OK to freeze | storage condition OK to freeze |
| shipped in ambient | shipped in wet ice | shipped in wet ice | shipped in wet ice |
Storage Class
11 - Combustible Solids
WGK
WGK 3
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