Skip to Content
Merck
All Photos(1)

Key Documents

860582C

Avanti

06:0 SM (d18:1/6:0)

Avanti Research - A Croda Brand 860582C

Synonym(s):

N-hexanoyl-D-erythro-sphingosylphosphorylcholine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C29H59N2O6P
CAS Number:
Molecular Weight:
562.76
UNSPSC Code:
12352211
NACRES:
NA.25

Pricing and availability is not currently available.

form

liquid

packaging

pkg of 1 × 1 mL (860582C-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860582C

concentration

5 mg/mL (860582C-5mg)

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C29H59N2O6P/c1-6-8-10-11-12-13-14-15-16-17-18-19-21-22-28(32)27(30-29(33)23-20-9-7-2)26-37-38(34,35)36-25-24-31(3,4)5/h21-22,27-28,32H,6-20,23-26H2,1-5H3,(H-,30,33,34,35)/b22-21+/t27-,28+/m0/s1

InChI key

AHZZHULAOVWYNO-RRKDMDGFSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
HPA066285MABC730HPA002018
conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

mouse

biological source

rabbit

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

-

product line

Prestige Antibodies® Powered by Atlas Antibodies

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

clone

polyclonal

clone

polyclonal

clone

5B8.2, monoclonal

clone

polyclonal

Application

06:0 SM (d18:1/6:0) may be used:
  • to study its effect on C-X-C motif chemokine ligand 12 (CXCL12)-induced cell migration using a transwell migration assay[1]
  • in liposomes to measure ostreolysin A (OlyA) binding in order to infer the effects of phosphatidylcholines (PCs) on sphingomyelin (SM)/cholesterol interactions[2]
  • as a component of lipid substrate mixture for substrate specificity studies of neutral sphingomyelinase fromTrypanosoma brucei[3]

Packaging

5 mL Clear Glass Sealed Ampule (860582C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3


  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Need A Sample COA?

    This is a sample Certificate of Analysis (COA) and may not represent a recently manufactured lot of this specific product.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Satoshi Asano et al.
    Molecular and cellular biology, 32(16), 3242-3252 (2012-06-13)
    Sphingomyelin synthase (SMS) catalyzes the formation of sphingomyelin, a major component of the plasma membrane and lipid rafts. To investigate the role of SMS in cell signaling and migration induced by binding of the chemokine CXCL12 to CXCR4, we used
    Emily A Dickie et al.
    Parasitology, 146(5), 604-616 (2018-11-06)
    The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals. Infections place a significant health and economic burden on developing nations in sub-Saharan Africa, but few effective anti-parasitic treatments are currently available. Hence, there is an urgent
    Shreya Endapally et al.
    Cell, 176(5), 1040-1053 (2019-02-05)
    Sphingomyelin and cholesterol are essential lipids that are enriched in plasma membranes of animal cells, where they interact to regulate membrane properties and many intracellular signaling processes. Despite intense study, the interaction between these lipids in membranes is not well
    Delphine Milhas et al.
    FEBS letters, 584(9), 1887-1894 (2009-10-28)
    The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service