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P2139

Poly(ethylene glycol)

greener alternative

average MN 8,000, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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500 g

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CLP 62,200
2 kg
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CLP 183,000
1 kg
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CLP 215,000

About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:

CLP 62,200


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Product Name

Poly(ethylene glycol), average mol wt 8,000, powder

form

powder

Quality Segment

mol wt

average mol wt 8,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

solubility

water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.

PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.

PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.

Features and Benefits

  • Highstructural flexibility
  • Biocompatibility
  • Amphiphilicity
  • Highhydration capacity
  • Devoidof any steric hindrance

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This Item
P4338202444P3265
form

powder

form

powder

form

powder

form

liquid

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mol wt

average mol wt 8,000

mol wt

average mol wt 3,350

mol wt

average Mn 3,350

mol wt

average mol wt 400

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

density

1.0962 g/mL at 60 °C, 1.0764 g/mL at 80 °C

density

1.204 g/mL at 25 °C

density

1.1254 g/cm3 at 20 °C, 1.0930 g/cm3 at 60 °C

solubility

water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)

solubility

water: soluble (PEG is soluble in water approximately 670 mg/ml, 20 °C)

solubility

-

solubility

water: 100 mg/mL

greener alternative category

Aligned

greener alternative category

Aligned

greener alternative category

Aligned

greener alternative category

Aligned


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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