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A16602

Sigma-Aldrich

DL-N-Acetylhomocysteine thiolactone

98%

Synonym(s):

2-Acetamido-4-mercaptobutyric acid γ-thiolactone

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About This Item

Empirical Formula (Hill Notation):
C6H9NO2S
CAS Number:
1195-16-0
Molecular Weight:
159.21
EC Number:
214-793-8
MDL number:
MFCD00005480
UNSPSC Code:
12352100
PubChem Substance ID:
24890578
NACRES:
NA.22

Assay

98%

form

powder

mp

109-111 °C (lit.)

SMILES string

CC(=O)NC1CCSC1=O

InChI

1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)

InChI key

NRFJZTXWLKPZAV-UHFFFAOYSA-N

Application

<ul>
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N Emonet et al.
Journal of photochemistry and photobiology. B, Biology, 40(1), 84-90 (1997-08-01)
The sensitivity of human dermal fibroblasts to UVA radiation has been linked to a decrease in intracellular glutathione (GSH) levels. GSH (gamma-glutamyl-cysteinyl-glycine) is a radical scavenger and a cofactor for protective enzymes such as selenium-dependent GSH peroxidases. In this study
G Papaccio et al.
Journal of cellular biochemistry, 71(4), 479-490 (1998-11-25)
This study showed that citiolone (CIT), a free radical scavenger, significantly increased superoxide dismutase (P < 0.001 vs. untreated NOD, NMMA-treated, and silica-treated animals), catalase (P < 0.01 vs. untreated NOD), and glutathione peroxidase (P < 0.001 vs. untreated NOD
J Kruuv et al.
Cryobiology, 30(3), 313-321 (1993-06-01)
The Arrhenius plot of inactivation (killing) rates of V-79 Chinese hamster cells exposed to hypothermia contains a break at about 8 degrees C, which corresponds to the minimum inactivation rate, implying that there are distinct hypothermic damage mechanisms above (Range
S D Vinay et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 9(4), 351-359 (1989-07-01)
Acid and alkaline phosphatase changes in various parts of the central nervous system (olfactory bulbs, cerebral hemispheres, cerebellum, medulla oblongata, and spinal cord) were analyzed during methylmercury chloride (MMC) treatment with a dose of 5 mg/kg/day body weight. The drug
C Bapu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 17(1), 75-80 (1998-03-07)
The aim of our investigation was to examine the efficacy of monothiols and vitamins in the restoration of ion-dependent ATPases in mice intoxicated with methylmercury chloride (MMC). A daily dose of glutathione (GSH), N-acetyl-DL-homocysteine thiolactone (NAHT), vitamin B complex, or
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