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724823

Sigma-Aldrich

Poly(N-isopropylacrylamide), amine terminated

average Mn 2,500 (T)

Synonym(s):

NIPAM polymer, PNIPAM-NH2, Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

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1 G
CLP 108,000
5 G
CLP 424,000

CLP 108,000


Estimated to ship onMay 26, 2025


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1 G
CLP 108,000
5 G
CLP 424,000

About This Item

Linear Formula:
H(C6H11NO)nSCH2CH2NH2
UNSPSC Code:
12162002
NACRES:
NA.23

CLP 108,000


Estimated to ship onMay 26, 2025


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form

solid

mol wt

Mn 2000-3000 (by HCL Titration)

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Application

Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The amine functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

Immunosuppressive tumor-associated myeloid cells (TAMC) are responsible for glioblastoma (GBM) resistance to immunotherapies and existing standard of care treatments. This mini-review highlights recent progress in implementing nanotechnology in advancing TAMC-targeted therapies for GBM.

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