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H0138

Sigma-Aldrich

Haptoglobin Human, Phenotype 1-1

98-100%, essentially salt-free, lyophilized powder

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human

Quality Level

Assay

98-100%

form

essentially salt-free, lyophilized powder

technique(s)

cell culture | mammalian: suitable

capacity

≥0.5 mg/mg (hemoglobin)

solubility

H2O: soluble 10 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... HP(3240)

Other Notes

Occurs as 3 major phenotypes: type 1-1, type 2-1, type 2-2.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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SNA delegates study COAR recommendations.
C Grimaldi et al.
The American nurse, 21(5), 5-5 (1989-05-01)
Eiko Shimada et al.
Transfusion, 47(12), 2315-2321 (2007-09-04)
Congenital haptoglobin deficiency is a risk factor for anaphylactic nonhemolytic transfusion reactions in Japan. The deleted allele of the haptoglobin gene, Hp(del), which causes congenital haptoglobin deficiency, has also been observed in other Northeast Asian populations, such as Korean and
Laust Dupont et al.
Progress in transplantation (Aliso Viejo, Calif.), 27(4), 386-391 (2017-12-01)
Cardiovascular disease is the leading cause of death in renal transplant recipients. An association between haptoglobin genotype 2-2 and cardiovascular disease has been found in patients with diabetes mellitus and liver transplant recipients. To date, the role of haptoglobin genotype
I B Ross et al.
Journal of neurotrauma, 8(4), 229-238 (1991-01-01)
Previously in our laboratory, nimodipine was effective in reversing posttraumatic ischemia and promoting electrophysiologic recovery in a rat spinal cord injury (SCI) model. However, these beneficial effects were achieved when nimodipine was combined with adjuvant therapy to reverse posttraumatic hypotension
Juan A Moreno et al.
Arteriosclerosis, thrombosis, and vascular biology, 30(6), 1253-1262 (2010-03-20)
In addition to its role in the clearance of haptoglobin-hemoglobin (Hp-Hb) complexes, CD163 is a macrophage scavenger receptor for tumor necrosis factor-like weak inducer of apoptosis (TWEAK). We recently reported that the CD163/TWEAK plasma ratio could be a potential biomarker

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