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D4266

Sigma-Aldrich

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
Molecular Weight:
307.49
Beilstein:
3967284
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

Assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable
protein purification: suitable
protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

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General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Application

3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.
  • Solubilization of oleosins.
Zwitterionic detergent used for protein solubilization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Solubilization conditions for hydrophobic membrane protein, oleosin, in soybeans
Kim, H., et al.
Biotechnology and Bioprocess Engineering: BBE, 12, 542-542 (2007)
Synthesis and surface-active properties of sulfobetaine-type zwitterionic gemini surfactants.
Yoshimura T, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 273(1), 208-212 (2006)
Effects of long-chains of zwitterionic micelles on binding constants of triflusal and acetylsalicylic acid.
Ferrit M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 345(1), 26-30 (2009)
L I Hochstein et al.
Biochemical and biophysical research communications, 147(1), 295-300 (1987-08-31)
A membrane-bound ATPase from Halobacterium saccharovorum was solubilized using sodium deoxycholate and Zwittergent 3-10 and purified by hydrophobic and ammonium sulfate-mediated chromatography. The enzyme, which had a molecular mass of 350 kDa, was composed of two major (87 and 60
Katarzyna Derwinska et al.
Analytica chimica acta, 592(2), 132-138 (2007-05-22)
Hydrogels are considered an optimum material for protein chip surfaces, since they provide a quasi-liquid environment which allows protein activity to be maintained and shows good spot morphology as well as excellent immobilization capacity. In the following, we present a

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