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DEAE-Dextran

average mol wt 500,000

Synonym(s):

Diethylaminoethyl-Dextran

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About This Item

CAS Number:
9015-73-0
UNSPSC Code:
12171500
NACRES:
NA.32

form

powder

mol wt

average mol wt 500,000

composition

nitrogen content, 2.5-4.5%

loss

≤10% loss on drying

storage temp.

−20°C

InChI

1S/C11H14O2/c1-3-8-13-11(12)10-6-4-9(2)5-7-10/h4-7H,3,8H2,1-2H3

InChI key

LRNBWFXCDULFQF-UHFFFAOYSA-N

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General description

DEAE-Dextran is used as mediator in DNA transfection procedures. It is considered to be simple and effective.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.
Felgner P L, et al.
Proceedings of the National Academy of Sciences of the USA, 84(21), 7413-7417 (1987)
Synthetic DNA delivery systems.
Luo D and Saltzman W M
Nature Biotechnology, 18(1), 33-33 (2000)
Joanne Marie M Del Rosario et al.
Frontiers in immunology, 11, 627-627 (2020-06-18)
Cross-subtype neutralizing single domain antibodies against influenza present new opportunities for immunoprophylaxis and pandemic preparedness. Their simple modular structure and single open reading frame format are highly amenable to gene therapy-mediated delivery. We have previously described R1a-B6, an alpaca-derived single

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