31395

Dextran sulfate sodium salt from Leuconostoc spp.

M_r ~500,000

• CAS Number: 9011-18-1
• UNSPSC Code: 12352201
• NACRES: NA.21
• MDL number: MFCD00081551

Properties

• biological source: (Leuconostoc spp.)
• Quality Segment: 200
• form: powder
• mol wt: M_r ~500,000
• composition: Sulfur Content, 16.0-19.0% (dry basis)
• manufacturer/tradename: EDQM
• useful pH range: 6.0-8.0 (10 g/L)
• solubility: H₂O: freely soluble 50 mg/mL, clear
• anion traces: chloride (Cl^-): ≤100 mg/kg
• cation traces: Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Mg: ≤100 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
• storage temp.: room temp

Description

Application

Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions.[1] It was used for releasing DNA from DNA-histone complexes.[2]

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.[3][4]The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.[5][6]

Preparation Note

prepared from dextran with M_r ~500,000

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)