05019

7-Diethylamino-3-[N-(2-maleimidoethyl)carbamoyl]coumarin

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

• Synonym(s): MDCC
• Empirical Formula (Hill Notation): C₂₀H₂₁N₃O₅
• CAS Number: 156571-46-9
• Molecular Weight: 383.40
• UNSPSC Code: 12352116
• PubChem Substance ID: 329748005
• NACRES: NA.32
• MDL number: MFCD07366642

Properties

• product line: BioReagent
• assay: ≥97.0% (HPLC)
• suitability: suitable for fluorescence
• SMILES string: CCN(CC)c1ccc2C=C(C(=O)NCCN3C(=O)C=CC3=O)C(=O)Oc2c1
• InChI: 1S/C20H21N3O5/c1-3-22(4-2)14-6-5-13-11-15(20(27)28-16(13)12-14)19(26)21-9-10-23-17(24)7-8-18(23)25/h5-8,11-12H,3-4,9-10H2,1-2H3,(H,21,26)
• InChI key: IXQPRUQVJIJUEB-UHFFFAOYSA-N

Description

Application

Thiol-reactive probe for protein labelling

7-Diethylamino-3-[N-(2-maleimidoethyl)carbamoyl]coumarin is utilized as a fluoresencent biological sensing device . Used for real-time measurements for the release of inorganic phosphates during enzymatic reaction when MDCC is conjugated to a mutant phosphate-binding protein . Also, utilized for intramolecular fluorescence energy transfer (FRET) experiments .

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves