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S9390

Sigma-Aldrich

Sodium phosphate dibasic heptahydrate

ACS reagent, 98.0-102.0%

Synonym(s):

Disodium hydrogen phosphate heptahydrate, Disodium phosphate

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About This Item

Linear Formula:
Na2HPO4 · 7H2O
CAS Number:
Molecular Weight:
268.07
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

vapor density

4.9 (vs air)

Assay

98.0-102.0%

form

powder

impurities

≤0.005% Insoluble matter

pH

8.7-9.3 (25 °C, 5% in solution)

density

1.68 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.005%

cation traces

Fe: ≤0.001%
heavy metals: ≤0.001% (by ICP)

SMILES string

O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2

InChI key

PYLIXCKOHOHGKQ-UHFFFAOYSA-L

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General description

Sodium phosphate dibasic heptahydrate is a hydrated form of disodium phosphate (DSP) or disodium hydrogen orthophosphate. DSP is widely used as a pH regulator and saline laxative.

Application

A mixture of sodium phosphate dibasic heptahydrate, potassium phosphate monobasic, and NaCl in deionized water is used for the preparation of phosphate-buffered saline (PBS, pH 7.4). PBS is used as a buffer solution in biological research to keep the pH constant.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Irina Petrova et al.
Scientific reports, 9(1), 8745-8745 (2019-06-21)
Circulating cancer markers are metabolic products found in body fluids of cancer patients, which are specific for a certain type of malignant tumors. Cancer marker detection plays a key role in cancer diagnosis, treatment, and disease monitoring. The growing need
Christian M Schürch et al.
Cell, 182(5), 1341-1359 (2020-08-09)
Antitumoral immunity requires organized, spatially nuanced interactions between components of the immune tumor microenvironment (iTME). Understanding this coordinated behavior in effective versus ineffective tumor control will advance immunotherapies. We re-engineered co-detection by indexing (CODEX) for paraffin-embedded tissue microarrays, enabling simultaneous
Sebastian Baumann et al.
Science advances, 6(11), eaaz1588-eaaz1588 (2020-03-24)
Through the asymmetric distribution of messenger RNAs (mRNAs), cells spatially regulate gene expression to create cytoplasmic domains with specialized functions. In neurons, mRNA localization is required for essential processes such as cell polarization, migration, and synaptic plasticity underlying long-term memory
Ziyi Yin et al.
Autophagy, 16(5), 900-916 (2019-07-18)
Cells are faced with various stresses during their growth and development, and autophagy is a degradative process in which cells can break down their own components to recycle macromolecules and provide energy under these stresses. For pathogenic fungi that utilize
Matthew H Crouthamel et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(11), 2625-2632 (2013-08-24)
Elevated serum phosphate has emerged as a major risk factor for vascular calcification. The sodium-dependent phosphate cotransporter, PiT-1, was previously shown to be required for phosphate-induced osteogenic differentiation and calcification of cultured human vascular smooth muscle cells (VSMCs), but its

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