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S0882

Sigma-Aldrich

Sodium selenate

≥95% (elemental analysis)

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About This Item

Linear Formula:
Na2SeO4
CAS Number:
13410-01-0
Molecular Weight:
188.94
EC Number:
236-501-8
MDL number:
MFCD00003490
UNSPSC Code:
12352302
PubChem Substance ID:
329824181
NACRES:
NA.55

Quality Level

200

Assay

≥95% (elemental analysis)

form

powder or crystals

pH

5.5-7.5 (25 °C, 18.9 g/L)

SMILES string

[Na+].[Na+].[O-][Se]([O-])(=O)=O

InChI

1S/2Na.H2O4Se/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

InChI key

MHQOTKLEMKRJIR-UHFFFAOYSA-L

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Application


  • Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway.: This study demonstrates that selenium nanoparticles, including sodium selenate, mitigate acute kidney injury caused by ischemia reperfusion. The nanoparticles modulate key pathways, offering potential therapeutic applications in renal injury treatment (Wang et al., 2022).

  • Phosphoproteomic profiling of selenate-treated Alzheimer′s disease model cells.: This research provides a detailed phosphoproteomic profile of Alzheimer′s disease model cells treated with sodium selenate, uncovering its effects on protein phosphorylation and implications for neuroprotection (Chen et al., 2014).

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - STOT RE 2

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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W C Stewart et al.
Journal of animal science, 90(2), 577-584 (2011-10-04)
Adequate Se transfer from ewes to lambs is important to prevent Se-deficiency diseases. To evaluate how different chemical forms of Se administered at comparative dosages to mature ewes affect Se status of their lambs, 240 ewes were divided into 8
Janet van Eersel et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(31), 13888-13893 (2010-07-21)
Alzheimer's disease (AD) brains are characterized by amyloid-beta-containing plaques and hyperphosphorylated tau-containing neurofibrillary tangles (NFTs); however, in frontotemporal dementia, the tau pathology manifests in the absence of overt amyloid-beta plaques. Therapeutic strategies so far have primarily been targeting amyloid-beta, although
J A Hall et al.
Journal of animal science, 90(2), 568-576 (2011-10-04)
Although the essentiality of dietary Se for sheep has been known for decades, the chemical source and Se dosage for optimal health remain unclear. In the United States, the Food and Drug Administration (FDA) regulates Se supplementation, regardless of the
Beatrice Pezzarossa et al.
Journal of the science of food and agriculture, 92(4), 781-786 (2011-09-29)
We investigated the effects of the foliar and fruit application of sodium selenate on selenium (Se) accumulation, fruit growth and ripening in peach and pear. Trials were conducted in two growing seasons. In 2008 selenate was applied at a rate
Nigel C Jones et al.
Neurobiology of disease, 45(3), 897-901 (2011-12-21)
Tau hyperphosphorylation has been implicated in the pathogenesis of a variety of forms of human epilepsy. Here we investigated whether treatment with sodium selenate, a drug which reduces pathological hyperphosphorylated tau by enhancement of PP2A activity, would inhibit seizures in
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