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Supelco

TEPP

PESTANAL®, analytical standard

Synonym(s):

Tetraethyl pyrophosphate, Tetraethyl diphosphate

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About This Item

Empirical Formula (Hill Notation):
C8H20O7P2
CAS Number:
Molecular Weight:
290.19
Beilstein:
1714017
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)OP(=O)(OCC)OCC

InChI

1S/C8H20O7P2/c1-5-11-16(9,12-6-2)15-17(10,13-7-3)14-8-4/h5-8H2,1-4H3

InChI key

IDCBOTIENDVCBQ-UHFFFAOYSA-N

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General description

TEPP (Tetraethyl pyrophosphate, Pestanal) is highly toxic in nature both by skin absorption and inhalation. It is an organic phosphate pesticide, acting acts as an inhibitor of cholinesterase. It is soluble in water and is slowly decomposed by water. It may be found as a dry mixture or in the liquid state.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C


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J U Patel et al.
Journal of pharmaceutical sciences, 83(10), 1477-1481 (1994-10-01)
An O-(saccharinylmethyl) prodrug was synthesized to improve the poor oral potency of the phenolic drug 17 beta-estradiol. This O-(imidomethyl) type of prodrug was designed to undergo chemical hydrolysis and to be a poor substrate for enzymatic hydrolysis. At 37 degrees
[Etiology of peptic ulcer under the influence of cholinesterase poisons].
R JAQUES
Helvetica physiologica et pharmacologica acta, 12(2), C 24-C 26 (1954-01-01)
Studies on the mechanism of action of DFP and TEPP.
B P McNAMARA et al.
The Journal of pharmacology and experimental therapeutics, 110(2), 232-240 (1954-02-01)
Tetraethyl pyrophosphate in the myasthenia gravis.
O J NOVOTA
Missouri medicine, 49(2), 133-134 (1952-02-01)
Reversal of the actions of tetraethyl pyrophosphate in surviving mammalian tissue.
B B ROY et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 89(2), 255-258 (1955-06-01)

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