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860398P

Avanti

18:0-d35 Lyso PC

Avanti Research - A Croda Brand 860398P, powder

Synonym(s):

1-stearoyl-d35-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C26H19NO7PD35
CAS Number:
Molecular Weight:
558.90
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (860398P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860398P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Lysophosphatidylcholine (Lyso PC) is a bioactive proinflammatory phospholipid and a component of oxidized low-density lipoprotein (Ox-LDL). It is produced during various pathological activities.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso PC) on acylation by yeast protein Ypr140w yields phosphatidylcholine (PC). Lyso PC alters functions in a numerous cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages, and T-cells and leads to the development of atherosclerosis and inflammatory diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860398P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ypr140wp,?the yeast tafazzin', displays a mitochondrial lysophosphatidylcholine (lyso-PC) acyltransferase activity related to triacylglycerol and mitochondrial lipid synthesis
Testet E, et al.
The Biochemical Journal, 387 (2005)
Role of Lysophosphatidylcholine (LPC) in Atherosclerosis
Takayuki M, et al.
Current Medicinal Chemistry, 14, 3209-3220 (2007)

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