56413
2-Pyridinol 1-oxide
≥98.0% (N)
Synonym(s):
1-Hydroxy-2-pyridone, 2-Hydroxypyridine 1-oxide, HOPO
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About This Item
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Quality Level
Assay
≥98.0% (N)
form
solid
mp
147-152 °C
SMILES string
Oc1cccc[n+]1[O-]
InChI
1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H
InChI key
JVHZMYAXZUIZKS-UHFFFAOYSA-N
Related Categories
General description
2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.
Application
2-Pyridinol 1-oxide can be used:
- To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.
- To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
- In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
212.0 °F - closed cup
Flash Point(C)
100 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Structure and Behavior of Organic Analytical Reagents. Formation Constants of Transition Metal Complexes of 2-Hydroxypyridine-1-Oxide and 2-Mercaptopyridine-1-Oxide.
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875. N-oxides and related compounds. Part V. The tautomerism of 2-and 4-amino-and-hydroxy-pyridine 1-oxide.
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