543292

IR-783

Dye content 90 %

• Synonym(s): 2-[2-[2-Chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium hydroxide, inner salt sodium salt
• Empirical Formula (Hill Notation): C₃₈H₄₆ClN₂NaO₆S₂
• CAS Number: 115970-66-6
• Molecular Weight: 749.35
• MDL number: MFCD03427057
• UNSPSC Code: 12352103
• PubChem Substance ID: 57651464
• NACRES: NA.23

Properties

• form: solid
• composition: Dye content, 90%
• mp: 209-212 °C (lit.)
• λmax: 782 nm
• SMILES string: [Na+].CC1(C)\C(=C\C=C2/CCCC(\C=C\C3=[N+](CCCCS([O-])(=O)=O)c4ccccc4C3(C)C)=C2Cl)N(CCCCS([O-])(=O)=O)c5ccccc15
• InChI: 1S/C38H47ClN2O6S2.Na/c1-37(2)30-16-5-7-18-32(30)40(24-9-11-26-48(42,43)44)34(37)22-20-28-14-13-15-29(36(28)39)21-23-35-38(3,4)31-17-6-8-19-33(31)41(35)25-10-12-27-49(45,46)47;/h5-8,16-23H,9-15,24-27H2,1-4H3,(H-,42,43,44,45,46,47);/q;+1/p-1
• InChI key: QQIQAVJARACLHE-UHFFFAOYSA-M

Description

General description

IR-783 is a near-infrared (NIR) dye with an extinction coefficient of 157000 M⁻¹cm⁻¹ and quantum yield of 0.11. Its excitation wavelength is in the range of 768-784 nm in saline.

Application

IR-783 can be used as a starting material in the synthesis of IR-808 dye for biological applications. It can also be used in the formation of NIR fluorescent human serum albumin nanoparticles for the detection of a tumor. It finds potential usage as a contrasting agent for the multimodal in vivo imaging.

Features and Benefits

Water soluble, laser and near-IR dye

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves