427519

2-Methylglutaronitrile

99%

• Synonym(s): α-Methylglutarodinitrile, α-Methylglutaronitrile, 1,3-Dicyanobutane, 2,4-Dicyanobutane, 2-Methylpentanedinitrile, Diacrylonitrile
• Linear Formula: NCCH(CH₃)CH₂CH₂CN
• CAS Number: 4553-62-2
• Molecular Weight: 108.14
• Beilstein: 1741955
• EC Number: 224-923-5
• MDL number: MFCD00001875
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866765
• NACRES: NA.22

Properties

• Assay: 99%
• form: liquid
• impurities: <0.1% benzene
• refractive index: n20/D 1.434 (lit.)
• bp: 269-271 °C (lit.)
• mp: −45 °C (lit.)
• solubility: water: soluble
• density: 0.95 g/mL at 25 °C (lit.)
• functional group: nitrile
• SMILES string: CC(CCC#N)C#N
• InChI: 1S/C6H8N2/c1-6(5-8)3-2-4-7/h6H,2-3H2,1H3
• InChI key: FPPLREPCQJZDAQ-UHFFFAOYSA-N

Description

General description

2-Methylglutaronitrile (MGN) is an aliphatic dinitrile. It is a high boiling solvent mainly used in the fiber industry. It is formed as a byproduct during the synthesis of adiponitrile. Synthesis of β-picoline using a mixture of 2-methylglutaronitrile and 2-ethylsuccinonitrile in the presence of silica-supported palladium, rhodium and platinum catalysts by vapour phase hydrogenation has been studied. Its core electron binding energy (CEBE) has been calculated via density functional theory (DFT). It has been reported to undergo hydrolysis catalyzed by nitrilase to form 4-cyanopentanoic acid.

Application

2-Methylglutaronitrile (MGN) may be used in the synthesis of 1,5-dimethyl-2-piperidone (1,5-DMPD) by chemoenzymatic process.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H311,H330
• Precautionary Statements: P260 - P264 - P271 - P280 - P302 + P352 + P312 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 239.0 °F - closed cup
• Flash Point(C): 115 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves